Ronald T Acton Selected Research

Iron Overload

12/2023	Platelet counts in HFE p.C282Y/p.C282Y and wt/wt post-screening clinical evaluation participants.
4/2023	Non-alcoholic fatty liver disease in hemochromatosis probands with iron overload and HFE p.C282Y/p.C282Y.
6/2022	HLA-A*03, the hemochromatosis ancestral haplotype, and phenotypes of referred hemochromatosis probands with HFE p.C282Y homozygosity.
1/2017	Diabetes in HFE Hemochromatosis.
12/2015	HFE gene: Structure, function, mutations, and associated iron abnormalities.
7/2013	Association between celiac disease and iron deficiency in Caucasians, but not non-Caucasians.
1/2013	Effects of highly conserved major histocompatibility complex (MHC) extended haplotypes on iron and low CD8+ T lymphocyte phenotypes in HFE C282Y homozygous hemochromatosis patients from three geographically distant areas.
4/2012	Increased risk of death from iron overload among 422 treated probands with HFE hemochromatosis and serum levels of ferritin greater than 1000 μg/L at diagnosis.
1/2012	Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations.
3/2011	Genome-wide association study identifies genetic loci associated with iron deficiency.

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Ronald T Acton Research Topics

Disease

43	Hemochromatosis (Bronze Diabetes) 01/2024 - 10/2002
39	Iron Overload 12/2023 - 02/2003
9	Fibrosis (Cirrhosis) 01/2024 - 01/2005
6	Infections 01/2020 - 07/2003
5	Hyperferritinemia 01/2022 - 04/2007
5	Insulin Resistance 01/2018 - 01/2005
4	Respiratory Tract Infections (Respiratory Tract Infection) 01/2020 - 01/2016
4	Common Variable Immunodeficiency 05/2017 - 06/2003
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2023 - 03/2015
3	Anemia 01/2022 - 11/2003
3	Hypersensitivity (Allergy) 01/2020 - 01/2016
3	Iron Deficiencies 07/2013 - 03/2011
3	Cardiomyopathies (Cardiomyopathy) 04/2012 - 07/2002
2	Fatigue 12/2023 - 05/2017
2	Type 2 Diabetes Mellitus (MODY) 04/2023 - 01/2017
2	Non-alcoholic Fatty Liver Disease 04/2023 - 01/2014
2	Hepatitis B 01/2022 - 01/2018
2	Hypertrophy 03/2016 - 01/2016
2	Hepatomegaly 03/2016 - 01/2016
2	Hypothyroidism 01/2016 - 01/2016
2	Diabetes Mellitus 01/2016 - 03/2015
2	Hepatitis 01/2014 - 07/2006
2	Liver Failure 04/2012 - 07/2009
2	Siderosis 04/2012 - 07/2009
2	Liver Diseases (Liver Disease) 08/2007 - 07/2006
1	Hyperpigmentation 12/2023
1	Hypertension (High Blood Pressure) 04/2023
1	Hyperlipidemias (Hyperlipidemia) 04/2023
1	Bacterial Infections (Bacterial Infection) 01/2019
1	Interstitial Cystitis (Interstitial Cystitis, Chronic) 05/2017
1	Fibromyalgia (Fibrositis) 05/2017
1	Urinary Tract Infections (Urinary Tract Infection) 01/2016
1	Joint Diseases (Joint Disease) 01/2014
1	Liver Neoplasms (Liver Cancer) 04/2012
1	Wounds and Injuries (Trauma) 10/2009
1	Soft Tissue Infections 10/2009
1	Granuloma 05/2009
1	Liver Cirrhosis (Hepatic Cirrhosis) 05/2009
1	Portal Hypertension 05/2009
1	Chronic Renal Insufficiency 04/2009
1	Hemorrhage 04/2009
1	Confusion (Bewilderment) 11/2007
1	Inflammation (Inflammations) 01/2005
1	Multiple Endocrine Neoplasia Type 2b (MEN 3) 01/2005
1	Coronary Disease (Coronary Heart Disease) 01/2005
1	Melanoma (Melanoma, Malignant) 08/2004
1	Hemoglobinopathies 11/2003
1	Thalassemia 11/2003
1	Chronic Hepatitis C 11/2003
1	Vibrio vulnificus infection 09/2003
1	IgA Deficiency 07/2003

Drug/Important Bio-Agent (IBA)

34	IronIBA 12/2023 - 02/2003
26	Ferritins (Ferritin)IBA 12/2023 - 01/2005
18	Transferrin (beta 2 Transferrin)IBA 12/2023 - 01/2005
12	HLA-A Antigens (HLA-A)IBA 01/2024 - 10/2002
8	HLA Antigens (Human Leukocyte Antigens)IBA 01/2024 - 01/2005
7	Immunoglobulin G (IgG)IBA 01/2024 - 06/2003
6	Aspartate Aminotransferases (Aspartate Transaminase)IBA 04/2023 - 04/2012
4	Alanine (L-Alanine)FDA Link 04/2023 - 04/2012
4	DNA (Deoxyribonucleic Acid)IBA 01/2012 - 02/2003
3	C-Reactive ProteinIBA 12/2023 - 01/2016
3	Immunoglobulin M (IgM)IBA 01/2020 - 07/2003
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020 - 01/2016
3	metal transporting protein 1 (ferroportin)IBA 09/2007 - 11/2003
2	Hemoglobins (Hemoglobin)IBA 12/2023 - 10/2007
2	Immunoglobulin A (IgA)IBA 01/2020 - 01/2016
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 01/2016
2	Immunoglobulins (Immunoglobulin)IBA 05/2017 - 07/2003
2	Ethanol (Ethyl Alcohol)IBA 01/2014 - 11/2003
1	23-valent pneumococcal capsular polysaccharide vaccineIBA 01/2020
1	Polysaccharides (Glycans)IBA 01/2020
1	HepcidinsIBA 01/2019
1	Insulin (Novolin)FDA Link 01/2018
1	Immunoglobulin IsotypesIBA 05/2017
1	HLA-A29 antigenIBA 05/2017
1	Hemochromatosis ProteinIBA 12/2015
1	Alanine Transaminase (SGPT)IBA 01/2014
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2010
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 05/2009
1	Warfarin (Coumadin)FDA LinkGeneric 04/2009
1	Carrier Proteins (Binding Protein)IBA 03/2009
1	Heme (Haem)IBA 03/2009
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 08/2008
1	Thyroxine (Levothyroxine)FDA LinkGeneric 08/2008
1	Complementary DNA (cDNA)IBA 09/2007
1	Apolipoproteins E (ApoE)IBA 01/2005
1	Blood Glucose (Blood Sugar)IBA 01/2005
1	HLA-DQB1 antigen (HLA DQB1)IBA 01/2005
1	very low density lipoprotein triglycerideIBA 01/2005
1	ElementsIBA 01/2005
1	HLA-DRB1 Chains (HLA DRB1)IBA 01/2005
1	VLDL LipoproteinsIBA 01/2005
1	ApolipoproteinsIBA 01/2005
1	HLA-DRB1*04 antigenIBA 08/2004
1	Saccharated Ferric Oxide (Venofer)FDA Link 09/2003
1	Erythropoietin FDA Link 09/2003

Therapy/Procedure

6	Therapeutics 01/2020 - 07/2002
1	Debridement 10/2009
1	Skin Transplantation (Skin Grafting) 10/2009
1	Renal Dialysis (Hemodialysis) 09/2003